ALEJANDRO HUERTA SAQUERO



DATOS GENERALES NOMBRAMIENTOS
Nombre completo   ALEJANDRO HUERTA SAQUERO
Máximo nivel de estudios   DOCTORADO
Antigüedad académica en la UNAM   22 años

Vigente   INVESTIGADOR TITULAR B TC Definitivo
Centro de Nanociencias y Nanotecnología en la UNAM
Desde 16-10-2021
ESTIMULOS, PROGRAMAS, PREMIOS Y RECONOCIMIENTOS
* SNI II2023
* SNI I2013 - 2022
* SNI I2009
* PRIDE C2012 - 2022
* PASPA Estancias Sabáticas2021 - 2022

INFORMACIÓN DE PUBLICACIONES
Firmas  
Huerta-Saquero A. HuertaSaquero, A Huerta-Saquero, A Huerta-Saquero, A. Huerta-Saquero, Alejandro
ID's SCOPUS  
6506456387
ORCID's  
0000-0002-0156-6773
Áreas de conocimiento  
Biochemistry and molecular biology Biology Biophysics Biotechnology & applied microbiology Biotechnology and applied microbiology
Computer science, interdisciplinary applications Chemistry, medicinal Chemistry, multidisciplinary Ecology Environmental sciences
Infectious diseases Materials science, multidisciplinary Microbiology Multidisciplinary sciences Nanoscience and nanotechnology
Neurosciences Pharmacology and pharmacy Polymer science Toxicology Agricultural and Biological Sciences (miscellaneous)
Agronomy and Crop Science Applied Microbiology and Biotechnology Chemical engineering (miscellaneous) Ecology Electrical and Electronic Engineering
Energy (miscellaneous) Materials Science (miscellaneous) Medicine (miscellaneous) Microbiology Microbiology (medical)
Multidisciplinary Organic chemistry Parasitology Pharmaceutical science Pharmacology, toxicology and pharmaceutics (miscellaneous)
Polymers and plastics Pollution Toxicology
Coautorías con entidades de la UNAM  
  • Centro de Nanociencias y Nanotecnología en la UNAM
  • Centro de Física Aplicada y Tecnología Avanzada
  • Instituto de Química
  • Instituto de Investigaciones en Matemáticas Aplicadas y en Sistemas
  • Instituto de Biotecnología
  • Facultad de Ciencias
  • Facultad de Química
  • Facultad de Estudios Superiores "Iztacala"
Revistas en las que ha publicado  (27):
  1. Acs Omega, Estados Unidos America (2020)
  2. ANTIBIOTICS-BASEL, Suiza (2022)
  3. APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH, Hungria (2015)
  4. Applied Nanoscience, Arabia Saudi (2018)
  5. BIOCHEMICAL GENETICS, Estados Unidos America (1996)
  6. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, (1999)
  7. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, Países Bajos (2004)
  8. BIOENGINEERED, Estados Unidos America (2013)
  9. Computational Biology And Chemistry, Estados Unidos America (2011, 2015)
  10. CURRENT MEDICINAL CHEMISTRY, (2020)
  11. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, Alemania (2016)
  12. FRONTIERS IN MICROBIOLOGY, Suiza (2023)
  13. INFECTION AND IMMUNITY, Estados Unidos America (2024)
  14. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, Países Bajos (2017, 2020)
  15. INTERNATIONAL JOURNAL OF NANOTECHNOLOGY, Suiza (2016)
  16. JOURNAL OF BACTERIOLOGY, Estados Unidos America (2005, 2010, 2012)
  17. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, (2012)
  18. MACROMOLECULAR BIOSCIENCE, Alemania (2017)
  19. Microbiology Spectrum, Estados Unidos America (2023)
  20. MICROBIOLOGYOPEN, Estados Unidos America (2021)
  21. Nano, Singapur (2016)
  22. NEUROSCIENCE LETTERS, Irlanda (2006)
  23. PEERJ, Reino Unido (2020)
  24. Pharmaceutics, Suiza (2021, 2023)
  25. PLOS ONE, Estados Unidos America (2016, 2019, 2020)
  26. PROTEIN EXPRESSION AND PURIFICATION, Estados Unidos America (2001)
  27. TOXICOLOGY LETTERS, Irlanda (2016, 2017)


Documentos indexados (WoS y Scopus)

# Título del documento Autores Año Rista Fuente Citas WoS Citas Scopus
1Decoration of Burkholderia Hcp1 protein to virus-like particles as a vaccine delivery platformCoautor: Huerta-Saquero A., Khakhum N., Baruch-Torres N., Stockton J.L., et al.2024INFECTION AND IMMUNITYWoS-id: 001162402400001
Scopus-id: 2-s2.0-85187723544
00
2GrlR, a negative regulator in enteropathogenic E. coli, also represses the expression of LEE virulence genes independently of its interaction with its cognate partner GrlA2ᵒ autor: Huerta-Saquero, Alejandro, Lara-Ochoa, Cristina, Medrano-Lopez, Abraham, Deng, Wanyin, et al.2023FRONTIERS IN MICROBIOLOGYWoS-id: 000941644300001
Scopus-id: 2-s2.0-85149488011
02
3P22-Based Nanovaccines against Enterohemorrhagic Escherichia coli1ᵉʳ autor: Huerta-Saquero, Alejandro, Chapartegui-Gonzalez, Itziar, Bowser, Sarah, Khakhum, Nittaya, et al.2023Microbiology SpectrumWoS-id: 000954043400001
Scopus-id: 2-s2.0-85154063187
04
4A Novel Formulation of Asparaginase Encapsulated into Virus-like Particles of Brome Mosaic Virus: In Vitro and In Vivo EvidenceCoautor: Huerta-Saquero, Alejandro, Villanueva-Flores, Francisca, Pastor, Ana Ruth, Palomares, Laura A.2023PharmaceuticsWoS-id: 001074286500001
Scopus-id: 2-s2.0-85172467430
00
5Metabolomic Profiling of the Responses of Planktonic and Biofilm Vibrio cholerae to Silver NanoparticlesCoautor: Huerta-Saquero, Alejandro, Meza-Villezcas, Anaid, Carballo-Castaneda, Rommel A., Moreno-Ulloa, Aldo2022ANTIBIOTICS-BASELWoS-id: 000880692300001
Scopus-id: 2-s2.0-85141701931
01
6Metagenomic analysis and antimicrobial activity of two fermented milk kefir samplesCoautor: Huerta-Saquero, Alejandro, Tenorio-Salgado, Silvia, Castelan-Sanchez, Hugo G., Davila-Ramos, Sonia, et al.2021MICROBIOLOGYOPENWoS-id: 000656486900002
Scopus-id: 2-s2.0-85105490466
1318
7Asparaginase-Phage P22 Nanoreactors: Toward a Biobetter Development for Acute Lymphoblastic Leukemia TreatmentCoautor: Huerta-Saquero, Alejandro, Diaz-Barriga, Cristina, Villanueva-Flores, Francisca, Quester, Katrin, et al.2021PharmaceuticsWoS-id: 000662433000001
Scopus-id: 2-s2.0-85105202347
1113
8Encapsulation of Asparaginase as a Promising Strategy to Improve In Vivo Drug PerformanceCoautor: Huerta-Saquero, Alejandro, Villanueva-Flores, Francisca, Zarate-Romero, Andres, Torres, Alfredo G.2021PharmaceuticsWoS-id: 000727516800001
Scopus-id: 2-s2.0-85120347781
57
9Nanopartiele-plasma Membrane interactions: Thermodynamics, Toxicity and Cellular ResponseCoautor y autor de correspondencia: Huerta-Saquero, Alejandro, Rodriguez-Hernandez, Ana G., Vazquez-Duhalt, Rafael2020CURRENT MEDICINAL CHEMISTRYWoS-id: 000540216200005
Scopus-id: 2-s2.0-85077740031
1116
10Deciphering the functional diversity of DNA-binding transcription factors in Bacteria and Archaea organismsCoautor: Huerta-Saquero A., Flores-Bautista E., Hernandez-Guerrero R., Tenorio-Salgado S., et al.2020PLOS ONEWoS-id: 000564080300094
Scopus-id: 2-s2.0-85089817268
1014
11Deep eutectic solvent-assisted phase separation in chitosan solutions for the production of 3D monoliths and films with tailored porosities2ᵒ autor: Huerta-Saquero A., Delgado-Rangel L.H., Eufracio-García N., Meza-Villezcas A., et al.2020INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESWoS-id: 000588093700389
Scopus-id: 2-s2.0-85090581666
1114
12Identification of L-asparaginases from Streptomyces strains with competitive activity and immunogenic profiles: A bioinformatic approachCoautor: Huerta-Saquero, Alejandro, Gonzalez-Torres, Ivan, Perez-Rueda, Ernesto, Evangelista-Martinez, Zahaed, et al.2020PEERJWoS-id: 000589179400003
Scopus-id: 2-s2.0-85096093183
57
13Beyond the Nanomaterials Approach: Influence of Culture Conditions on the Stability and Antimicrobial Activity of Silver NanoparticlesCoautor y autor de correspondencia: Huerta-Saquero, Alejandro, Vazquez-Munoz, Roberto, Bogdanchikova, Nina2020Acs OmegaWoS-id: 000592385200004
Scopus-id: 2-s2.0-85096018629
1626
14Effect of antimicrobial nanocomposites on Vibrio cholerae lifestyles: Pellicle biofilm, planktonic and surface-attached biofilmCoautor: Huerta-Saquero, Alejandro, Meza-Villezcas, Anaid, Gallego-Hernandez, Ana L., Yildiz, Fitnat H., et al.2019PLOS ONEWoS-id: 000471234500040
Scopus-id: 2-s2.0-85067210901
1216
15Enhancement of antibiotics antimicrobial activity due to the silver nanoparticles impact on the cell membraneCoautor: Huerta-Saquero A., Vazquez-Muñoz R., Meza-Villezcas A., Fournier P.G.J., et al.2019PLOS ONEWoS-id: 000532697200032
Scopus-id: 2-s2.0-85074692147
132182
16Surface modification of protein enhances encapsulation in chitosan nanoparticlesCoautor: Huerta-Saquero, Alejandro, Koyani, Rina D., Andrade, Mariana, Quester, Katrin, et al.2018Applied NanoscienceWoS-id: 000442669600028
Scopus-id: 2-s2.0-85060279989
910
17Toxicity of silver nanoparticles in biological systems: Does the complexity of biological systems matter?Coautor: Huerta-Saquero, Alejandro, Vazquez-Munoz, Roberto, Borrego, Belen, Juarez-Moreno, Karla, et al.2017TOXICOLOGY LETTERSWoS-id: 000403985800002
Scopus-id: 2-s2.0-85019434906
140172
18Cytochrome P450 Bioconjugate as a Nanovehicle for Improved Chemotherapy TreatmentCoautor: Huerta-Saquero, Alejandro, Quester, Katrin, Juarez-Moreno, Karla, Secundino, Isamel, et al.2017MACROMOLECULAR BIOSCIENCEWoS-id: 000404298200008
Scopus-id: 2-s2.0-85006241376
1113
19PEGylation of cytochrome P450 enhances its biocatalytic performance for pesticide transformationCoautor: Huerta-Saquero A., Alejo-González K., Quester K., Hanson E., et al.2017INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESWoS-id: 000414882900018
Scopus-id: 2-s2.0-85023622873
45
20Silver nanoparticles composition for treatment of distemper in dogsCoautor: Huerta-Saquero, Alejandro, Bogdanchikova, Nina, Vazquez-Munoz, Roberto, Pena-Jasso, Antonio, et al.2016INTERNATIONAL JOURNAL OF NANOTECHNOLOGYWoS-id: 000372079100019
Scopus-id: 2-s2.0-84958748338
2729
21Sophisticated and Spontaneous Template-Free Organization of Silica Nanoparticles during StorageCoautor: Huerta-Saquero, Alejandro, Bogdanchikova, Nina, Martynyuk, Oxana, Vazquez-Gomez, Roberto L., et al.2016NanoWoS-id: 000373991700001
Scopus-id: 2-s2.0-84975833230
01
22Biotransformation of petroleum asphaltenes and high molecular weight polycyclic aromatic hydrocarbons by Neosartorya fischeriCoautor: Huerta-Saquero, Alejandro, Lorena Hernandez-Lopez, E., Perezgasga, Lucia, Mourino-Perez, Rosa, et al.2016ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCHWoS-id: 000377021500042
Scopus-id: 2-s2.0-84958772391
1218
23Synthesis and Complete Antimicrobial Characterization of CEOBACTER, an Ag-Based NanocompositeCoautor: Huerta-Saquero, A., Jaime-Acuna, O. E., Meza-Villezcas, A., Vasquez-Pena, M., et al.2016PLOS ONEWoS-id: 000387615200071
Scopus-id: 2-s2.0-84994568496
1014
24Toxicity of silver nanoparticles in biological systems: Does the complexity of biological systems matter?Coautor: Huerta-Saquero, A., Vazquez-Munoz, R., Borrego, B., Juarez-Moreno, K. O., et al.2016TOXICOLOGY LETTERSWoS-id: 000396848100473
50
25LIPID PEROXIDATION AND PROTEIN OXIDATION INDUCED BY DIFFERENT NANOPARTICLES IN ZEBRAFISH ORGANSCoautor: HuertaSaquero, A, Carrillo, Y, TorresDuarte, C, Oviedo, MJ, et al.2015APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCHWoS-id: 000354731000007
Scopus-id: 2-s2.0-84926334723
25
26The functional landscape bound to the transcription factors of Escherichia coli K-12Coautor: Huerta-Saquero A., Pérez-Rueda E., Tenorio-Salgado S., Balderas-Martínez Y.I., et al.2015Computational Biology And ChemistryWoS-id: 000364897700010
Scopus-id: 2-s2.0-84935843963
1414
27Rhizobium etli asparaginase II An alternative for acute lymphoblastic leukemia (ALL) treatment (vol 22, pg 292, 2012)1ᵉʳ autor: Huerta-Saquero, A, Evangelista-Martinez, Z, Moreno-Enriquez, A, Perez-Rueda, E2013BIOENGINEEREDWoS-id: 000336900300015
Scopus-id: 2-s2.0-84877712964
89
28Biochemical characterization of recombinant L-asparaginase (AnsA) from Rhizobium etli, a member of an increasing Rhizobial-type family of L-asparaginasesCoautor: Huerta-Saquero A., Angélica M.-E., Evangelista-Martínez Z., González-Mondragón E.G., et al.2012JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGYWoS-id: 000302190800002
Scopus-id: 2-s2.0-84930479563
3437
29A Distinct Regulatory Sequence Is Essential for the Expression of a Subset of nle Genes in Attaching and Effacing Escherichia coliCoautor: Huerta-Saquero, A, Garcia-Angulo, VA, Martinez-Santos, VI, Villasenor, T, et al.2012JOURNAL OF BACTERIOLOGYWoS-id: 000309490600011
Scopus-id: 2-s2.0-84868553607
1617
30New insights on gene regulation in archaea2ᵒ autor: Huerta-Saquero, A, Tenorio-Salgado, S, Perez-Rueda, E2011Computational Biology And ChemistryWoS-id: 000298274400003
Scopus-id: 2-s2.0-80055000248
79
31Molecular Characterization of GrlA, a Specific Positive Regulator of ler Expression in Enteropathogenic Escherichia coliCoautor: Huerta-Saquero, A, Jimenez, R, Cruz-Migoni, SB, Bustamante, VH, et al.2010JOURNAL OF BACTERIOLOGYWoS-id: 000281327900011
Scopus-id: 2-s2.0-77956536808
2629
32Recovery after a traumatic brain injury depends on diurnal variations. Effect of cystatin CCoautor: Huerta-Saquero A., Martinez-Vargas M., Gonzalez-Rivera R., Soto-Nuñez M., et al.2006NEUROSCIENCE LETTERSWoS-id: 000237843300005
Scopus-id: 2-s2.0-33646123297
1415
33The stringent response is required for amino acid and nitrate utilization, nod factor regulation, nodulation, and nitrogen fixation in Rhizobium etliCoautor: Huerta-Saquero A., Calderón-Flores A., Du Pont G., Merchant-Larios H., et al.2005JOURNAL OF BACTERIOLOGYWoS-id: 000230716800003
Scopus-id: 2-s2.0-22544483526
3437
34Regulation of transcription and activity of Rhizobium etli glutaminase a1ᵉʳ autor: Huerta-Saquero A., Calderón-Flores A., Díaz-Villaseñor A., Du Pont G., et al.2004BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTSWoS-id: 000223122000012
Scopus-id: 2-s2.0-3242789502
23
35Overexpression and purification of Rhizobium etli glutaminase A by recombinant and conventional procedures. A comparative study of enzymatic properties1ᵉʳ autor: Huerta-Saquero A., Calderón J., Arreguín R., Calderón-Flores A., et al.2001PROTEIN EXPRESSION AND PURIFICATIONWoS-id: 000167881900009
Scopus-id: 2-s2.0-0035718598
1419
36Sequence and molecular analysis of the Rhizobium etli glsA gene, encoding a thermolabile glutaminase2ᵒ autor: Huerta-Saquero A., Calderón J., Du Pont G., Durán S.1999BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSIONWoS-id: 000079355400017
Scopus-id: 2-s2.0-0033582951
1012
37Identification of two glutaminases in Rhizobium etliCoautor: Huerta-Saquero A., Durán S., Sánchez-Linares L., Du Pont G., et al.1996BIOCHEMICAL GENETICSWoS-id: A1996WU46900006
Scopus-id: 2-s2.0-0030439531
1619

Proyectos

# Nombre Participantes Convocatoria Fecha Inicio Fecha Fin
1Efecto microbicida sobre patogénesis de vibrio.ALEJANDRO HUERTA SAQUERO,
Recursos CONACYT01-07-201531-03-2018
2Nanoreactores enzimáticos para el combate de enfermedades: alternativas para el tratamiento de la leucemia linfocítica aguda.ALEJANDRO HUERTA SAQUERO,
Recursos PAPIIT01-02-201831-12-2020
3Efecto de los nanomateriales antimicrobianos en la expresión de factores de virulencia de Vibrio choleare.ALEJANDRO HUERTA SAQUERO,
Recursos CONACYT28-09-201927-09-2021

Participación en Comités de Tesis

# Título del documento Tipo de Tesis Sinodales Autores Año Entidad Url
1Síntesis y caracterización de nanomateriales antimicrobianos para su uso en la conservación de patrimonio culturalTesis de LicenciaturaALEJANDRO HUERTA SAQUERO; Martínez Rodríguez, Ramiro Martín; 2017Centro de Nanociencias y Nanotecnología en la UNAM,
2Caracterización funcional de SepD en Escherichia Coli enteropatógenaTesis de LicenciaturaALEJANDRO HUERTA SAQUERO; Huesca Alatorre, Fabian; 2009Instituto de Biotecnología,
3Purificacion y caracterizacion de la Asparaginasa II de Rhizobium etllTesis de LicenciaturaALEJANDRO HUERTA SAQUERO; Moreno Enriquez, Angélica; 2004

Docencia Impartida

# Entidad Nivel Asignatura Año Semestre Alumnos
1Centro de Nanociencias y Nanotecnología en la UNAMLicenciaturaLABORATORIO DE MICROBIOLOGIA20182019-18
2Centro de Nanociencias y Nanotecnología en la UNAMLicenciaturaBIOLOGIA MOLECULAR20152016-12
3Centro de Nanociencias y Nanotecnología en la UNAMLicenciaturaBIOLOGIA MOLECULAR20142015-16
4Centro de Nanociencias y Nanotecnología en la UNAMLicenciaturaLABORATORIO DE MICROBIOLOGIA20132014-16

Descargar PDF