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Título del libro: Sporotrichosis: New Developments And Future Prospects
Título del capítulo: Components and Virulence Factors of the Sporothrix schenckii Species Complex

Autores UNAM:
ARMANDO PEREZ TORRES;
Autores externos:

Idioma:
Inglés
Año de publicación:
2015
Palabras clave:

Antigens; Cell wall; Sporothrix schenckii complex; Virulence factors


Resumen:

Sporotrichosis is a fungal infection caused by the Sporothrix schenckii species complex, which includes species of clinical relevance such as S. brasiliensis, S. schenckii sensu stricto, S. globosa, S. mexicana, and S. luriei. When S. schenckii was discovered as a species complex with several entities, the similarities and differences among these pathogenic species began to be studied with respect to their virulence, susceptibility to antifungal agents, protein production, and immunogenicity, among other characteristics. Still, little is known about the factors that contribute to the virulence of this species complex and about the mechanisms involved in the establishment and development of sporotrichosis. This chapter reviews the virulence factors and main components described for the S. schenckii complex, which include fungal dimorphism, thermotolerance, melanin production, secretion of proteases, and cell surface components. © Springer International Publishing Switzerland 2015.


Entidades citadas de la UNAM: