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Título del libro: Handbook Of Ion Channels
Título del capítulo: Patch clamping and single-channel analysis

Autores UNAM:
LEON DAVID ISLAS SUAREZ;
Autores externos:

Idioma:

Año de publicación:
2015
Resumen:

Neher and Sakmann rst reported single-channel patch-clamp recordings in the late 1970s (Neher and Sakmann, 1976; Neher et al., 1978). Since the publication of these and the seminal papers of Hamill et al. (1981) and Colquhoun and Hawkes (1981, 1982), our understanding of ion channels as molecular machines has increased dramatically, but, although automatic patch clamps and microfabricated and polydimethylsiloxane polymer (PDMS)-based pipette-free systems (Fertig et al., 2002; Klemic et al., 2002) are now available, the essential tools of single-channel recording and analysis have not changed dramatically. © 2015 by Taylor & Francis Group, LLC.


Entidades citadas de la UNAM: