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Título del libro: Retinal And Choroidal Manifestations Of Selected Systemic Diseases
Título del capítulo: Vogt-Koyanagi-Harada disease

Autores UNAM:
MARIA DE LOURDES ARELLANES GARCIA;
Autores externos:

Idioma:

Año de publicación:
2013
Palabras clave:

Immune disorders; Immunosuppressors; In flammation; Major histocompatibility complex; Sunset glow fundus; Vogt-Koyanagi-Harada disease


Resumen:

Vogt-Koyanagi-Harada disease is a bilateral granulomatous panuveitis, generally symmetrical, associated to extraocular manifestations such as poliosis, vitiligo, alopecia, central nervous system, and auditory signs. It is considered an autoimmune disease, mediated by T cells, against melanocytes of uveal tract, skin, central nervous system, and inner ear. A genetic predisposition has been suggested. Patients have no history of ocular trauma and no clinical or laboratory evidence of other ocular or systemic disease. Therapy includes early, high doses of systemic steroids. Immunomodulatory therapy has also been used with good results. © Springer Science+Business Media New York 2013.


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