®®®® SIIA Público

Título del libro: Autoimmunity, Covid-19, Post-Covid19 Syndrome And Covid-19 Vaccination
Título del capítulo: COVID-19: the impact of the cytokine storm on the immune-neuroendocrine system

Autores UNAM:
LUIS JAVIER JARA QUEZADA; GABRIELA MEDINA GARCIA; MARIA DEL PILAR CRUZ DOMINGUEZ; OLGA LIDIA VERA LASTRA;
Autores externos:

Idioma:

Año de publicación:
2022
Palabras clave:

Autoimmunity; COVID-19; Cytokine storm; Immune-neuroendocrine system; Post-COVID-19


Resumen:

The term ?cytokine storm? was first proposed in 1993 by Ferrara et al. In 1991, Chatenaud described a systemic clinical picture called ?Cytokine Release Syndrome? very similar to ?Cytokine Storm Syndrome? so these terms can be used synonymously. During the COVID-19 pandemic, high-risk individuals (>65 years, with comorbidities) may develop cytokine storms as a consequence of multiorgan involvement seen during the acute and post-COVID-19 phases. On the other hand, the term immune neuroendocrine system was first proposed by Besedovsky H et al. Evidences obtained during COVID-19 infection demonstrated that SARS-CoV-2 infections can affect the immune neuroendocrine system, both in its invasion stage of different organs and tissues and in the recovery stage. This damage is caused by viral infection and/or cytokine storm. This chapter analyzes the devastating effect of SARS-CoV-2 infection and the cytokine storm on the immune neuroendocrine system. These evidences may lead to new therapeutic proposals. © 2023 Elsevier Inc. All rights reserved.


Entidades citadas de la UNAM: