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Título del libro: Microbial Bioreactors For Industrial Molecules
Título del capítulo: Microbial bioreactors at different scales for the alginate production by azotobacter vinelandii

Autores UNAM:
DANIEL GENARO SEGURA GONZALEZ; CARLOS FELIPE PEÑA MALACARA;
Autores externos:

Idioma:

Año de publicación:
2023
Palabras clave:

A. vinelandii cultures; Alginate production; Azotobacter vinelandii; Bacterial production; Bioreactor scale; Cultivation modalities; Genetic regulation; Pharmaceutical industries; Polyhydroxy butyrate


Resumen:

Alginates are extracted from seaweed and are mainly applied in the food and pharmaceutical industries. These polymers can also be produced by bacteria of the genera Pseudomonas and Azotobacter as a component of the extracellular matrix. Azotobacter vinelandii is a Gram-negative, strictly aerobic bacterium capable of fixing atmospheric nitrogen. This bacterium produces two polymers of industrial interest, polyhydroxy butyrate and alginate. This chapter addresses the following topics: research concerning alginate biosynthesis and genetic regulation, bacterial production on a bioreactor scale, different cultivation modalities for the production of alginate, as well as the influence of cultivation parameters on the quantity and quality of the alginate. It discusses the main studies on the scaling-up of alginate production. The chapter summarizes the effects of cultivation modalities on alginate production in A. vinelandii cultures, which has been widely studied in shake flasks to small fermenters at the laboratory level. © 2023 John Wiley & Sons Ltd. All rights reserved.


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