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Título del libro: Engineering Of Microorganisms For The Production Of Chemicals And Biofuels From Renewable Resources
Título del capítulo: Evolutionary engineering of microorganisms to overcome toxicity during lignocellulose hydrolysates utilization

Autores UNAM:
JOSE UTRILLA CARRERI;
Autores externos:

Idioma:
Inglés
Año de publicación:
2017
Palabras clave:

Adaptive laboratory evolution; Inhibitors tolerance; Toxicity mechanisms


Resumen:

Microbial chemicals and fuels production from renewable resources requires the development of biocatalysts that can tolerate toxic chemicals produced during the lignocellulosic hydrolyzation process and also tolerate the end product toxicity. Evolutionary engineering makes use of adaptive strategies and selection procedures to generate and study mutations that will increase tolerance to harmful chemicals and therefore increase productivity and titer in such processes. In this chapter, we will review recent advances in evolutionary engineering strategies, their results and challenges to generate better microorganisms for the production of chemicals and fuels from lignocellulosic hydrolysates. © 2017 Springer International Publishing AG.


Entidades citadas de la UNAM: