HELADIA SALGADO OSORIO



DATOS GENERALES NOMBRAMIENTOS
Nombre completo   HELADIA SALGADO OSORIO
Máximo nivel de estudios   LICENCIATURA
Antigüedad académica en la UNAM   25 años

Vigente   TECNICO ACADEMICO TITULAR C TC Definitivo
Centro de Ciencias Genómicas
Desde 01-01-2018
ESTIMULOS, PROGRAMAS, PREMIOS Y RECONOCIMIENTOS
* SNI I - 2023
* PRIDE D - 2022

INFORMACIÓN DE PUBLICACIONES
Firmas  
Salgado H. Salgado, H Salgado, H. Salgado, Heladia
ID's SCOPUS  
7006032034
Áreas de conocimiento  
Biochemical research methods Biochemistry & molecular biology Biochemistry and molecular biology Biology Biophysics
Biotechnology & applied microbiology Cell biology Computer science, theory & methods Genetics & heredity Genetics and heredity
Jcs 2008 Mathematical & computational biology Mathematical and computational biology Microbiology Multidisciplinary sciences
Neurosciences Scie jcr Virology Agricultural and Biological Sciences (miscellaneous) Biophysics
Biotechnology Computational mathematics Computer Science (miscellaneous) Computer science applications Ecology, evolution, behavior and systematics
Genetics Medicine (miscellaneous) Microbiology Molecular Biology Multidisciplinary
Neuroscience (miscellaneous) Parasitology
Coautorías con entidades de la UNAM  
  • Consejo Técnico y Coordinación de la Investigación Científica
  • Centro de Ciencias Genómicas
  • Centro de Ciencias Aplicadas y Desarrollo Tecnológico
  • Laboratorio Internacional de Investigación Sobre el Genoma Humano
  • Instituto de Física
  • Instituto de Investigaciones Biomédicas
  • Instituto de Fisiología Celular
  • Instituto de Biotecnología
  • Facultad de Ciencias
  • Facultad de Medicina
  • Facultad de Química
Revistas en las que ha publicado  (27):
  1. BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, Países Bajos (2021)
  2. Bioinformatics, Reino Unido (1996, 1998, 2019, 2020)
  3. BIOTECHNOLOGY AND BIOENGINEERING, Estados Unidos America (2003)
  4. Bmc Bioinformatics, Reino Unido (2006, 2007)
  5. BMC BIOLOGY, Reino Unido (2018)
  6. Bmc Genomics, Reino Unido (2008)
  7. Current Protocols In Bioinformatics, Estados Unidos America (2018)
  8. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, Reino Unido (2013)
  9. FEBS LETTERS, Estados Unidos America (2007)
  10. Frontiers in Genetics, Suiza (2024)
  11. Gene, Países Bajos (2004)
  12. Genome Biology, (2003)
  13. INTEGR BIOL-UK, Reino Unido (2012)
  14. JOURNAL OF BACTERIOLOGY, Estados Unidos America (2008, 2009, 2014)
  15. JOURNAL OF MOLECULAR BIOLOGY, Estados Unidos America (2007)
  16. Lecture Notes in Artificial Intelligence, Suiza (2007)
  17. Methods in Molecular Biology, Estados Unidos America (2012)
  18. Microbial Genomics, (2022)
  19. Neuroreport, Estados Unidos America (2015)
  20. Neuroscience, Reino Unido (2008, 2009)
  21. NUCLEIC ACIDS RESEARCH, Reino Unido (1998, 1999, 2000, 2001, 2004, 2006, 2007, 2008, 2009, 2011, 2013, 2016, 2019, 2024)
  22. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing, (1997)
  23. PLOS ONE, Estados Unidos America (2009, 2013)
  24. PLOS PATHOGENS, Estados Unidos America (2017)
  25. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Estados Unidos America (2000)
  26. SCIENTIFIC REPORTS, Reino Unido (2016)
  27. TRENDS IN MICROBIOLOGY, Estados Unidos America (2006)


Documentos indexados (WoS y Scopus)

# Título del documento Autores Año Rista Fuente Citas WoS Citas Scopus
1RegulonDB v12.0:ã comprehensive resource of transcriptional regulation in E. coli K-121ᵉʳ autor: Salgado H., Gama-Castro S., Lara P., Mejia-Almonte C., et al.2024NUCLEIC ACIDS RESEARCHWoS-id: 001102810900001
Scopus-id: 2-s2.0-85181777832
11
2Flexible gold standards for transcription factor regulatory interactions in Escherichia coli K-12: architecture of evidence typesCoautor: Salgado H., Lara P., Gama-Castro S., Rioualen C., et al.2024Frontiers in GeneticsWoS-id: 001186999100001
Scopus-id: 2-s2.0-85188101282
00
3RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12Coautor: Salgado H., Tierrafría V.H., Rioualen C., Lara P., et al.2022Microbial GenomicsWoS-id: 000812938700011
Scopus-id: 2-s2.0-85130765382
1531
4Lisen&Curate: A platform to facilitate gathering textual evidence for curation of regulation of transcription initiation in bacteriaCoautor: Salgado H., Díaz-Rodríguez M., Lithgow-Serrano O., Guadarrama-García F., et al.2021BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMSWoS-id: 000703308500001
Scopus-id: 2-s2.0-85115326527
23
5Programmatic access to bacterial regulatory networks with regutoolsCoautor: Salgado, Heladia, Chavez, Joselyn, Barberena-Jonas, Carmina, Sotelo-Fonseca, Jesus E., et al.2020BioinformaticsWoS-id: 000606794200027
Scopus-id: 2-s2.0-85094220804
13
6RegulonDB v 10.5: tackling challenges to unify classic and high throughput knowledge of gene regulation in E. coli K-122ᵒ autor: Salgado H., Santos-Zavaleta A., Gama-Castro S., Sánchez-Pérez M., et al.2019NUCLEIC ACIDS RESEARCHWoS-id: 000462587400034
Scopus-id: 2-s2.0-85059797142
224235
7MCO: towards an ontology and unified vocabulary for a framework-based annotation of microbial growth conditionsCoautor: Salgado, H., Tierrafria, V. H., Mejia-Almonte, C., Camacho-Zaragoza, J. M., et al.2019BioinformaticsWoS-id: 000467227300017
Scopus-id: 2-s2.0-85062289226
33
8A unified resource for transcriptional regulation in Escherichia coli K-12 incorporating high-throughput-generated binding data into RegulonDB version 10.0Coautor: Salgado H., Santos-Zavaleta A., Sánchez-Pérez M., Velázquez-Ramírez D.A., et al.2018BMC BIOLOGYWoS-id: 000441842200001
Scopus-id: 2-s2.0-85051701959
3032
9Using RegulonDB, the Escherichia coli K-12 Gene Regulatory Transcriptional Network Database1ᵉʳ autor: Salgado H., Martínez-Flores I., Bustamante V.H., Alquicira-Hernández K., et al.2018Current Protocols In BioinformaticsScopus-id: 2-s2.0-85050792661
08
10The transcriptional regulator SsrB is involved in a molecular switch controlling virulence lifestyles of SalmonellaCoautor: Salgado H., Pérez-Morales D., Banda M.M., Elizabeth Chau, N. Y., et al.2017PLOS PATHOGENSWoS-id: 000406623700032
Scopus-id: 2-s2.0-85026880726
4043
11RegulonDB version 9.0: high-level integration of gene regulation, coexpression, motif clustering and beyond2ᵒ autor: Salgado, Heladia, Gama-Castro, Socorro, Santos-Zavaleta, Alberto, Ledezma-Tejeida, Daniela, et al.2016NUCLEIC ACIDS RESEARCHWoS-id: 000371261700018
Scopus-id: 2-s2.0-84976874666
334351
12In silico clustering of Salmonella global gene expression data reveals novel genes co-regulated with the SPI-1 virulence genes through HilDCoautor: Salgado, Heladia, Martinez-Flores, Irma, Perez-Morales, Deyanira, Sanchez-Perez, Mishael, et al.2016SCIENTIFIC REPORTSWoS-id: 000388557100003
Scopus-id: 2-s2.0-84998610822
1719
13Immobility time during the forced swimming test predicts sensitivity to amitriptyline, whereas traveled distance in the circular corridor indicates resistance to treatment in female Wistar ratsCoautor: Salgado H., Flores-Serrano A.G., Zaldívar-Rae J., Pineda J.C.2015NeuroreportWoS-id: 000350754300001
Scopus-id: 2-s2.0-84925136571
33
14In silico identification and experimental characterization of regulatory elements controlling the expression of the salmonella csrB and csrC genesCoautor: Salgado, H, Martinez, LC, Martinez-Flores, I, Fernandez-Mora, M, et al.2014JOURNAL OF BACTERIOLOGYWoS-id: 000332624300013
Scopus-id: 2-s2.0-84890942426
2727
15RegulonDB v8.0: Omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more1ᵉʳ autor: Salgado, H, Peralta-Gil, M, Gama-Castro, S, Santos-Zavaleta, A, et al.2013NUCLEIC ACIDS RESEARCHWoS-id: 000312893300028
Scopus-id: 2-s2.0-84876543942
325339
16Evidence classification of high-throughput protocols and confidence integration in RegulonDBCoautor: Salgado, H, Weiss, V, Medina-Rivera, A, Huerta, AM, et al.2013DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATIONWoS-id: 000316174600001
Scopus-id: 2-s2.0-84879348696
1216
17Transcription Factors in Escherichia coli Prefer the Holo ConformationCoautor: Salgado H., Balderas-Martínez Y.I., Savageau M., Pérez-Rueda E., et al.2013PLOS ONEWoS-id: 000320322400048
Scopus-id: 2-s2.0-84878913760
2023
18On the trail of EHEC/EAEC-unraveling the gene regulatory networks of human pathogenic Escherichia coli bacteriaCoautor: Salgado H., Pauling J., Rottger, R, Neuner A., et al.2012INTEGR BIOL-UKWoS-id: 000305694800003
Scopus-id: 2-s2.0-84863701397
67
19Extracting regulatory networks of escherichia coli from RegulonDB1ᵉʳ autor: Salgado H., Martínez-Flores I., López-Fuentes A., García-Sotelo J.S., et al.2012Methods in Molecular BiologyWoS-id: 000321878900011
Scopus-id: 2-s2.0-84855906633
1212
20RegulonDB version 7.0: Transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units)2ᵒ autor: Salgado H., Gama-Castro S., Peralta-Gil M., Santos-Zavaleta A., et al.2011NUCLEIC ACIDS RESEARCHWoS-id: 000285831700018
Scopus-id: 2-s2.0-78651299341
274293
21Theoretical and empirical quality assessment of transcription factor-binding motifsCoautor: Salgado H., Medina-Rivera A., Abreu-Goodger C., Thomas-Chollier M., et al.2011NUCLEIC ACIDS RESEARCHWoS-id: 000287257500010
Scopus-id: 2-s2.0-79951570672
4751
22Bioinformatics Resources for the Study of Gene Regulation in Bacteria2ᵒ autor: Salgado, H, Collado-Vides, J, Morett, E, Gama-Castro, S, et al.2009JOURNAL OF BACTERIOLOGYWoS-id: 000261628100002
Scopus-id: 2-s2.0-58149495994
2021
23Transcriptional regulation shapes the organization of genes on bacterial chromosomes2ᵒ autor: Salgado H., Janga S.C., Martínez-Antonio A.2009NUCLEIC ACIDS RESEARCHWoS-id: 000267441800025
Scopus-id: 2-s2.0-67649872023
5156
24Genome-Wide Identification of Transcription Start Sites, Promoters and Transcription Factor Binding Sites in E. coliCoautor: Salgado, H, Mendoza-Vargas, A, Olvera, L, Olvera, M, et al.2009PLOS ONEWoS-id: 000270880900016
Scopus-id: 2-s2.0-70449380939
192212
25DOPAMINE D-2-CLASS RECEPTOR SUPERSENSITIVITY AS REFLECTED IN Ca2+ CURRENT MODULATION IN NEOSTRIATAL NEURONSCoautor: Salgado, H, Prieto, GA, Perez-Burgos, A, Fiordelisio, T, et al.2009NeuroscienceWoS-id: 000271731700001
Scopus-id: 2-s2.0-70349748815
2427
26RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigationCoautor: Salgado, H, Gama-Castro, S, Jimenez-Jacinto, V, Peralta-Gil, M, et al.2008NUCLEIC ACIDS RESEARCHWoS-id: 000252545400022
Scopus-id: 2-s2.0-38549140094
371399
27The LysR-type transcriptional regulator LeuO controls expression of several genes in Salmonella enterica serovar typhiCoautor: Salgado, H, Hernandez-Lucas, I, Gallego-Hernandez, AL, Encarnacion, S, et al.2008JOURNAL OF BACTERIOLOGYWoS-id: 000253554300021
Scopus-id: 2-s2.0-39749126195
6871
28Immunity related genes in dipterans share common enrichment of AT-rich motifs in their 5 ' regulatory regions that are potentially involved in nucleosome formationCoautor: Salgado H., Hernandez-Romano J., Carlos-Rivera F.J., Lamadrid-Figueroa H., et al.2008Bmc GenomicsWoS-id: 000258139200001
Scopus-id: 2-s2.0-48549089600
33
29Muscarinic M(1) modulation of N and L types of calcium channels is mediated by protein kinase C in neostriatal neuronsCoautor: Salgado, H, Perez-Burgos, A, Perez-Rosello, T, Flores-Barrera, E, et al.2008NeuroscienceWoS-id: 000259213200007
Scopus-id: 2-s2.0-50549093535
2731
30Internal Versus External Effector and Transcription Factor Gene Pairs Differ in Their Relative Chromosomal Position in Escherichia coli2ᵒ autor: Salgado H., Janga S.C., Collado-Vides J., Martínez-Antonio A.2007JOURNAL OF MOLECULAR BIOLOGYWoS-id: 000245672500023
Scopus-id: 2-s2.0-33947420169
1213
31Conservation of transcriptional sensing systems in prokaryotes: A perspective from Escherichia coli1ᵉʳ autor: Salgado H., Martínez-Antonio A., Janga S.C.2007FEBS LETTERSWoS-id: 000248473200030
Scopus-id: 2-s2.0-34447278869
67
32Automatic reconstruction of a bacterial regulatory network using Natural Language Processing2ᵒ autor: Salgado H., Rodríguez-Penagos C., Martínez-Flores I., Collado-Vides J.2007Bmc BioinformaticsWoS-id: 000249274300002
Scopus-id: 2-s2.0-34548499877
3339
33Coordination logic of the sensing machinery in the transcriptional regulatory network of Escherichia coli2ᵒ autor: Salgado H., Janga S.C., Martínez-Antonio A., Collado-Vides J.2007NUCLEIC ACIDS RESEARCHWoS-id: 000251336000030
Scopus-id: 2-s2.0-36749095093
2218
34NLP-based curation of bacterial regulatory networks2ᵒ autor: Salgado H., Rodríguez-Penagos C., Martínez-Flores I., Collado-Vides J.2007Lecture Notes in Artificial IntelligenceScopus-id: 2-s2.0-37149056907
01
35Internal-sensing machinery directs the activity of the regulatory network in Escherichia coliCoautor: Salgado H., Martínez-Antonio A., Janga S.C., Collado-Vides J.2006TRENDS IN MICROBIOLOGYWoS-id: 000235123200007
Scopus-id: 2-s2.0-30344484891
6973
36The comprehensive updated regulatory network of Escherichia coli K-121ᵉʳ autor: Salgado H., Santos-Zavaleta A., Gama-Castro S., Peralta-Gil M., et al.2006Bmc BioinformaticsWoS-id: 000235550300001
Scopus-id: 2-s2.0-30644465547
5048
37RegulonDB (version 5.0): Escherichia coli K-12 transcriptional regulatory network, operon organization, and growth conditions.1ᵉʳ autor: Salgado H., Gama-Castro S., Peralta-Gil M., Díaz-Peredo E., et al.2006NUCLEIC ACIDS RESEARCHWoS-id: 000239307700086
Scopus-id: 2-s2.0-33644873438
265297
38RegulonDB (version 4.0): Transcriptional regulation, operon organization and growth conditions in Escherichia coli K-121ᵉʳ autor: Salgado H., Gama-Castro S., Martínez-Antonio A., Díaz-Peredo E., et al.2004NUCLEIC ACIDS RESEARCHWoS-id: 000188079000071
Scopus-id: 2-s2.0-9144270496
192226
39Distribution of minigenes in the bacteriophage lambda chromosome2ᵒ autor: Salgado H., Oviedo N.-A., Collado-Vides J., Guarneros G.2004GeneWoS-id: 000220856300012
Scopus-id: 2-s2.0-1642412681
32
40The mosaic structure of the symbiotic plasmid of Rhizobium etli CFN42 and its relation to other symbiotic genome compartments.Coautor: Salgado H., González V., Bustos P., Ramírez-Romero M.A., et al.2003Genome BiologyWoS-id: 000183720100006
Scopus-id: 2-s2.0-0037562601
124118
41Environmental Conditions and Transcriptional Regulation in Escherichia coli: A Physiological Integrative Approach2ᵒ autor: Salgado H., Martínez-Antonio A., Gama-Castro S., Gutiérrez-Ríos R.M., et al.2003BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000187634500003
Scopus-id: 2-s2.0-0348062847
1515
42RegulonDB (version 3.2): Transcriptional regulation and operon organization in Escherichia coli K-121ᵉʳ autor: Salgado H., Santos-Zavaleta A., Gama-Castro S., Millán-Zárate D., et al.2001NUCLEIC ACIDS RESEARCHWoS-id: 000166360300017
Scopus-id: 2-s2.0-0035162782
178190
43RegulonDB (version 3.0): Transcriptional regulation and operon organization in Escherichia coli K-121ᵉʳ autor: Salgado H., Santos-Zavaleta A., Gama-Castro S., Millán-Zárate D., et al.2000NUCLEIC ACIDS RESEARCHWoS-id: 000084896300016
Scopus-id: 2-s2.0-0033971476
5049
44Operons in Escherichia coli: Genomic analyses and predictions1ᵉʳ autor: Salgado H., Moreno-Hagelsieb G., Smith T.F., Collado-Vides J.2000PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAWoS-id: 000087526300076
Scopus-id: 2-s2.0-0034612277
270289
45RegulonDB (version 2.0): A database on transcriptional regulation in Escherichia coli1ᵉʳ autor: Salgado H., Santos A., Garza-Ramos U., Van Helden J., et al.1999NUCLEIC ACIDS RESEARCHWoS-id: 000077983000012
Scopus-id: 2-s2.0-0032947086
3133
46RegulonDB: A database on transcriptional regulation in Escherichia coli2ᵒ autor: Salgado H., Huerta A.M., Thieffry D., Collado-Vides J.1998NUCLEIC ACIDS RESEARCHScopus-id: 2-s2.0-0031811851
116152
47Prediction of transcriptional regulatory sites in the complete genome sequence of Escherichia coli K-122ᵒ autor: Salgado H., Thieffry D., Huerta A.M., Collado-Vides J.1998BioinformaticsScopus-id: 2-s2.0-0031827572
077
48Definite-clause grammars for the analysis of cis-regulatory regions in E. coli.Coautor: Salgado H., Thieffry D., Rosenblueth D.A., Huerta A.M., et al.1997Pacific Symposium On Biocomputing. Pacific Symposium On BiocomputingScopus-id: 2-s2.0-0031305541
03
49Syntactic recognition of regulatory regions in escherichia coliCoautor: Salgado H., Rosenblueth D.A., Thieffry D., Huerta A.M., et al.1996BioinformaticsScopus-id: 2-s2.0-0030474940
029

Docencia Impartida

# Entidad Nivel Asignatura Año Semestre Alumnos
1Instituto de BiotecnologíaLicenciaturaPRINCIPIOS DE ESTADISTICA20232023-28
2Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220232023-212
3Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 120222023-112
4Instituto de BiotecnologíaLicenciaturaSEMINARIO 120222023-18
5Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220222022-214
6Instituto de BiotecnologíaLicenciaturaPRINCIPIOS DE ESTADISTICA20222022-211
7Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 120212022-114
8Instituto de BiotecnologíaLicenciaturaPRINCIPIOS DE ESTADISTICA20212021-213
9Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220212021-223
10Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 120202021-123
11Instituto de BiotecnologíaLicenciaturaPRINCIPIOS DE ESTADISTICA20202020-228
12Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220202020-222
13Instituto de BiotecnologíaMaestríaCURSO IV20172018-18
14Facultad de QuímicaMaestríaCURSO IV20162016-21
15Facultad de QuímicaMaestríaCURSO III20152016-11
16Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220142014-218
17Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220132013-221
18Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220122012-222
19Facultad de QuímicaMaestríaCURSO III20112012-12
20Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220092009-228
21Instituto de BiotecnologíaLicenciaturaBIOINFORMATICA Y ESTADISTICA 220092009-235
22Instituto de BiotecnologíaLicenciaturaCOMPUTACION III20082008-235
23Instituto de BiotecnologíaLicenciaturaCOMPUTACION II20072008-136

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